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Blandy Flap

The Blandy flap is an eponymous urethral reconstructive technique attributed to Sir John Blandy (1927–2011), Professor of Urology at The London Hospital and a pioneering British urologist. The eponym refers to two distinct but related techniques:

  1. Female Blandy ventral vaginal flap urethroplasty / meatoplasty — an inverted U-shaped anterior vaginal wall advancement flap for distal female urethral stricture and meatal stenosis. This is the contemporary clinically dominant use and the focus of this page.[1][2][3]
  2. Male Blandy perineal urethrostomy / scrotal-skin perineal urethroplasty — a perineal stoma created from a pedicled scrotal-skin flap on the dartos pedicle for end-stage anterior urethral disease.

Sir John Blandy's contributions to urethral surgery, stone disease, and oncology are memorialized in the textbook Blandy's Urology (now in its 3rd edition).[4] The "Blandy technique" for female urethral stricture has been described as "the most common technique used" for this condition in the open-surgical era.[1]


Female Blandy Ventral Vaginal Flap Urethroplasty

Technique

A ventral meatoplasty / urethroplasty using the anterior vaginal wall as a local advancement flap to augment the strictured distal female urethra:

  1. Position — dorsal lithotomy; Foley catheter to identify the urethral lumen.
  2. Incision — an inverted U-shaped incision on the anterior vaginal wall, with the base of the U surrounding the urethral meatus and the arms extending proximally along the periurethral vaginal mucosa.
  3. Urethrotomy — the ventral (posterior) wall of the strictured urethra is incised longitudinally through the meatus and proximally through the full length of the stricture until healthy non-strictured urethral tissue is reached.
  4. Flap advancement — the U-shaped vaginal mucosal flap is advanced distally and sutured into the opened urethral defect, widening the urethral lumen by incorporating vaginal-wall tissue into the ventral urethral plate.
  5. Closure — flap sutured to urethral edges with absorbable suture; vaginal-wall donor site closed primarily; catheter for several days postoperatively.

The technique is conceptually analogous to the Heineke-Mikulicz principle — converting a longitudinal stricture into a wider lumen by incorporating adjacent tissue — and similar in philosophy to the male Orandi penile-skin onlay flap.[1][5]

Primary indication — female urethral stricture

Female urethral stricture is rare. Management options:

  • Urethral dilation — first-line but poor long-term success: 6% cure with dilation alone vs. 78–100% with urethroplasty[6]
  • Distal urethrectomy with advancement meatoplasty
  • Blandy ventral vaginal flap meatoplasty / urethroplasty
  • Lateral-based vaginal wall flap (Orandi-inspired modification)
  • Dorsal or ventral buccal mucosal graft (BMG) urethroplasty

The 2023 AUA Urethral Stricture Disease Guideline recommends offering urethroplasty over repeated dilation for female urethral stricture given the low efficacy of endoscopic treatment, with success rates of 69–95% across vaginal-flap and oral-mucosa-graft techniques.[7]

Outcomes

StudyTechniquenSuccessFollow-upNotes
Önol 2011[10]Anterior vaginal wall mucosa inlay10 (of 17 total)100% objective, 88% subjectiveMedian 24 moQmax 10.8 → 28.9 mL/s; PVR 120 → 30 mL
Hajebrahimi 2019[11]Anterior U-shaped vaginal flap14100% voiding improvementVariableQmax 15.8 mL/s postop; 2 developed SUI
Blaivas 2012[6]Vaginal flap urethroplasty9 (of 17 total)100% at 1 yr; 78% at 5 yrUp to 6 yrDilation only 6% success
Flisser & Blaivas 2003[12]Vaginal flap + pubovaginal sling7293% anatomicalMedian 1.5 yr87% continence cure / improvement
Kowalik 2014[13]VFU vs dorsal BMG10VFU 2 recurrences; BMG 0VariableBMG may have edge for durability
Spilotros 2017[14]BMG (14) vs vaginal flap (2)16BMG 93%; vaginal flap 100%VariableUrethroplasty far superior to dilation

Other female applications

Meatal reconstruction after vulvectomy

The Blandy-type vaginal advancement flap has been adapted for urethral meatus reconstruction after oncologic vulvectomy. In a 42-reconstruction series in 41 women after vulvectomy, anterior vaginal-wall advancement with V-Y inset into a posterior urethrotomy achieved excellent results with only 1 neomeatal stenosis. The V-Y inset prevents the circular-suture-line stenosis that follows simple advancement.[8]

Distal urethral stricture in transwomen

The inverted U-flap technique (derived from the Blandy concept) has been applied to neo-vaginal advancement flap urethroplasty in transwomen with distal urethral strictures. In 5 patients (3 inverted U-flap, 2 seven-flap), no recurrences were observed at median 37-month follow-up, with 100% patient satisfaction.[9]

Limitations and known drawbacks

  • Retrusive meatus — ventral advancement can result in a posteriorly displaced meatus with an inward-directed urinary stream, the principal criticism that motivated the Romero-Maroto lateral-based vaginal-wall flap modification (Orandi-inspired) which preserves orthotopic meatus position.[1]
  • Limited reach for proximal strictures — best suited for distal and meatal strictures; lateral-based vaginal flaps, dorsal BMG, or combined approaches are preferred for mid-urethral or longer strictures.[2][3]
  • Vaginal-tissue quality — depends on healthy, well-estrogenized vaginal tissue. Lichen sclerosus, vaginal atrophy, or prior radiation may compromise the flap and favor buccal mucosa.[2]
  • De novo SUI — vaginal-flap urethroplasty carries a ~10–15% SUI risk and may require a secondary anti-incontinence procedure.[6][15]

Comparison with alternative female-urethral-stricture techniques

TechniqueBest indicationAdvantagesDisadvantagesSuccess rate
Blandy (ventral vaginal flap)Distal / meatal strictureSimple; well-vascularized; no graft harvestRetrusive meatus; limited for proximal strictures78–100%
Lateral vaginal-wall flap (Orandi-type)Distal-to-mid strictureOrthotopic meatus; preserves stream directionRequires lateral pedicle dissection100% (small series)
Dorsal BMG onlayMid-to-proximal stricture; lichen sclerosusIndependent tissue source; durableOral donor-site morbidity; technically demanding69–93%
Ventral BMG + Martius flapMid stricture with poor vaginal tissueRobust vascular support; versatileTwo donor sites; more complex93–100%
Distal urethrectomy + advancement meatoplastyShort distal strictureSimple; definitiveShortens urethra; SUI risk80–90%
Vaginal-wall advancement (post-vulvectomy)Meatal reconstruction after vulvectomyPrevents circular stenosis with V-Y designSpecific to that setting95%

Male Blandy Perineal Urethrostomy

The "Blandy" eponym is also applied to the scrotal-skin perineal urethrostomy that creates a tension-free, well-vascularized permanent perineal stoma for end-stage anterior urethral stricture disease. A pedicled fasciocutaneous flap of perineal scrotal skin on the dartos pedicle is raised, the urethra is opened ventrally at the bulb, and the scrotal-skin flap is sutured into the urethrotomy to create a wide, mucocutaneous-mature perineal meatus with low restenosis risk.

GU applications:

  • Perineal urethrostomy — tension-free permanent perineal stoma
  • Anterior urethral onlay / inlay reconstruction in perineal / bulbar urethra when penile-skin or BMG options are exhausted

The technique is conceptually adjacent to the Johanson, Asopa, and Orandi penile-skin techniques but uses the proximal scrotal donor in place of preputial / shaft skin. Practical limitations include hair-bearing donor skin (consider epilation), unavailability after extensive scrotal surgery or Fournier's gangrene, and reduced reliability in heavily irradiated fields.


Key Takeaways

  1. The female Blandy ventral vaginal flap urethroplasty is the most commonly used open technique for distal female urethral stricture and meatal stenosis, with success rates of 78–100% depending on follow-up duration.
  2. The principal limitation is a tendency to create a retrusive meatus with an inward urinary stream — driving the development of lateral-based vaginal-flap modifications (Romero-Maroto) and dorsal BMG techniques.
  3. The 2023 AUA guideline recommends urethroplasty (vaginal flap or BMG) over repeated dilation (6% cure) for female urethral stricture.
  4. The Blandy flap is the vaginal-tissue option of first choice when local tissue is healthy, well-estrogenized, and the stricture is distal; reserve BMG for tissue-poor or proximal cases.
  5. The Blandy male perineal urethrostomy uses scrotal-skin pedicled flap on the dartos pedicle to create a permanent perineal stoma in end-stage anterior urethral disease.

See Also


References

1. Romero-Maroto J, Verdú-Verdú L, Gómez-Pérez L, et al. "Lateral-Based Anterior Vaginal Wall Flap in the Treatment of Female Urethral Stricture: Efficacy and Safety." Eur Urol. 2018;73(1):123–128. doi:10.1016/j.eururo.2016.09.029

2. Bouchard B, Campeau L. "Surgery for Female Urethral Stricture." Neurourol Urodyn. 2025;44(1):51–62. doi:10.1002/nau.25358

3. West C, Lawrence A. "Female Urethroplasty: Contemporary Thinking." World J Urol. 2019;37(4):619–629. doi:10.1007/s00345-018-2564-4

4. Watkin N, Kaul A. "Penis and Urethra Inflammation." Chapter 32, Blandy's Urology.

5. Simonato A, Varca V, Esposito M, Carmignani G. "Vaginal Flap Urethroplasty for Wide Female Stricture Disease." J Urol. 2010;184(4):1381–1385. doi:10.1016/j.juro.2010.06.042

6. Blaivas JG, Santos JA, Tsui JF, et al. "Management of Urethral Stricture in Women." J Urol. 2012;188(5):1778–1782. doi:10.1016/j.juro.2012.07.042

7. Wessells H, Morey A, Souter L, Rahimi L, Vanni A. "Urethral Stricture Disease Guideline Amendment (2023)." J Urol. 2023;210(1):64–71. doi:10.1097/JU.0000000000003482

8. Lange M, Hage JJ, Hartveld L, Zijlmans HJMAA, van Beurden M. "Reconstruction of the Meatus Urethrae After Oncologic Vulvectomy: Outcome of 42 Vaginal Flap Advancements in 41 Women." Ann Plast Surg. 2022;88(5):538–543. doi:10.1097/SAP.0000000000003048

9. Waterloos M, Hollebosch S, Verla W, et al. "Neo-Vaginal Advancement Flaps in the Treatment of Urethral Strictures in Transwomen." Urology. 2019;129:217–222. doi:10.1016/j.urology.2019.02.003

10. Önol FF, Antar B, Köse O, Erdem MR, Önol ŞY. "Techniques and Results of Urethroplasty for Female Urethral Strictures: Our Experience With 17 Patients." Urology. 2011;77(6):1318–1324. doi:10.1016/j.urology.2011.01.017

11. Hajebrahimi S, Maroufi H, Mostafaei H, Salehi-Pourmehr H. "Reconstruction of the Urethra With an Anterior Vaginal Mucosal Flap in Female Urethral Stricture." Int Urogynecol J. 2019;30(12):2055–2060. doi:10.1007/s00192-019-03910-3

12. Flisser AJ, Blaivas JG. "Outcome of Urethral Reconstructive Surgery in a Series of 74 Women." J Urol. 2003;169(6):2246–2249. doi:10.1097/01.ju.0000061763.88247.16

13. Kowalik C, Stoffel JT, Zinman L, Vanni AJ, Buckley JC. "Intermediate Outcomes After Female Urethral Reconstruction: Graft vs Flap." Urology. 2014;83(5):1181–1185. doi:10.1016/j.urology.2013.12.052

14. Spilotros M, Malde S, Solomon E, et al. "Female Urethral Stricture: A Contemporary Series." World J Urol. 2017;35(6):991–995. doi:10.1007/s00345-016-1947-7

15. Zumstein V, Dahlem R, Maurer V, et al. "Single-Stage Buccal Mucosal Graft Urethroplasty for Meatal Stenoses and Fossa Navicularis Strictures: A Monocentric Outcome Analysis and Literature Review on Alternative Treatment Options." World J Urol. 2020;38(10):2609–2620. doi:10.1007/s00345-019-03035-8