Female Vaginal Flap Urethroplasty (Blandy U-Flap)
The Blandy U-flap vaginal flap urethroplasty is the foundational ventral-onlay vaginal-flap technique for female urethral stricture (FUS) repair. A U-shaped anterior-vaginal-wall flap is mobilized on a proximal pedicle, the strictured urethra is opened ventrally, and the flap is inlaid into the urethrotomy defect to augment the urethral lumen.[1][2][3] It is the female counterpart of the male ventral-onlay urethroplasty.
Blandy U-flap geometry. (1) A U-shaped anterior-vaginal-wall flap with a proximal pedicle is raised over the strictured urethra and a ventral (6 o'clock) urethrotomy is planned. (2) The flap is inlaid into the opened urethra as a ventral onlay over a 16–18 Fr Foley, sutured to the native plate. The cross-section shows the result: native dorsal urethral plate above, vaginal-flap onlay ventrally. Being pedicled, the flap keeps its submucosal vascular plexus — no buccal-graft donor site. (Original WARWIKI schematic)
For the broader female-stricture treatment ladder, see Female DVIU and Urethral Dilation, Distal Urethrectomy with Advancement Meatoplasty, Lateral-Based Anterior Vaginal Wall Flap, Female Dorsal Onlay BMG, and Ventral Onlay BMG.
Eponym and Concept
Attributed to John Blandy. The U-flap design uses anterior vaginal wall as a pedicled flap (proximal base), preserving the submucosal vascular plexus, and avoids the donor-site morbidity of buccal mucosa.[1][3]
Indications
- FUS refractory to dilation or DVIU.[4][5]
- Distal and mid-urethral strictures (most common application).[6][7]
- Healthy, well-estrogenized anterior vaginal wall (no LS, no severe atrophy).[4][8]
- Selected longer / pan-urethral strictures in experienced hands.[9]
Contraindications / Limitations
- Lichen sclerosus or vaginal atrophy compromising the flap.[4][8]
- Prior pelvic radiation.
- Prior synthetic midurethral sling with periurethral scarring limiting flap mobilization.[7]
Technique
Dorsal lithotomy under regional or general anesthesia.[2][10]
- Cystourethroscopy — confirm location, length, and proximal urethra / bladder.
- Foley placement — identifies the urethral lumen and serves as a guide.[2]
- U-shaped vaginal incision — two parallel longitudinal incisions in the anterior vaginal wall flanking the urethra, beginning at the meatus and extending proximally past the stricture, joined distally around the meatus to create a U-shaped flap with a proximal pedicle.[2][3]
- Flap elevation — vaginal mucosal flap dissected off the periurethral tissue and reflected cephalad to expose the ventral urethra.[2]
- Ventral urethrotomy — longitudinal 6 o'clock incision through the full length of the stricture, extending into healthy mucosa proximally and distally.[2][10]
- Flap inlay — distal tip of the vaginal flap sutured to the proximal end of the urethrotomy with interrupted 4-0 / 5-0 polyglactin; lateral edges sutured to the lateral edges of the incised urethral mucosa to augment the ventral circumference.[2][10]
- Tubularization of the inner portion of the flap over a 16–18 Fr Foley to ensure adequate caliber.[2]
- Second-layer closure — outer flap layer or native vaginal wall edges closed as a watertight second layer.[2]
- Catheter — 10–21 days postoperatively (varies by series).[2][10]
Technical principles — pedicled (not free graft); U-width must allow tension-free augmentation; ventral approach preserves the dorsal urethral surface and pubourethral ligaments.[4][11][12]
Important Modifications
Lateral-based anterior vaginal wall flap (Romero-Maroto / Simonato)
Romero-Maroto 2018 and Simonato 2010 independently described a lateral-based rather than midline U-flap, inspired by the Orandi technique. The lateral pedicle better preserves the vascular axis; Simonato's variant adds partial de-epithelialization of the flap edges to promote cicatrization at the suture line and reduce fistula risk. Romero-Maroto specifically developed the modification because the classic Blandy U-flap produced retrusive meatus and inward urinary stream — a recognized functional limitation of the proximal-pedicled design.[1][9] See Lateral-Based Anterior Vaginal Wall Flap.
Gormley vaginal inlay flap
Simplified ventral-incision-and-inlay variant. Gormley 2010: 12 patients, follow-up 3 mo–9 yr, 100% subjective symptom relief, all able to catheterize 14 Fr, 0% de novo SUI.[10]
Blaivas vaginal flap reconstruction (urethral loss / neourethra)
For urethral loss rather than stricture: vaginal flap rolled into a tube to create a neourethra, covered with a Martius labial fat-pad flap, combined with pubovaginal sling. Blaivas-Heritz 1996: 49 women, continence in 87%.[13][14]
Outcomes
| Series | n | Technique | Success | Mean follow-up | De-novo SUI |
|---|---|---|---|---|---|
| Hajebrahimi 2019[2] | 14 | U-shaped vaginal flap | 100% (voiding improved) | — | 14% (2/14) |
| Gormley 2010[10] | 12 | Vaginal inlay flap | 100% (symptom relief) | 3 mo–9 yr | 0% |
| Romero-Maroto 2018[1] | 9 | Lateral-based vaginal flap | 100% (no recurrence) | 80.7 mo | 0% |
| Simonato 2010[9] | 6 | Lateral-pedicle vaginal flap | 83% (5/6) | 70.8 mo | 0% |
| Önol 2011[7] | 10 (of 17) | Anterior vaginal wall inlay | 100% objective | 24 mo (median) | not reported |
| Higuchi 2026[6] | 7 | VFU (various) | 57.1% (4/7) | 12 mo (median) | 0% |
| Blaivas 2012[15] | 9 | Vaginal flap | 100% at 1 yr; 78% at 5 yr | 1–11 yr | concurrent sling |
| Flisser-Blaivas 2003[16] | 72 | Vaginal flap ± sling | 93% anatomic | 1.5 yr (median) | concurrent sling |
Pooled vaginal-flap urethroplasty success in systematic reviews is 91–93% at 32–42 months mean follow-up.[5]
The Retrusive-Meatus / Spraying Problem
The defining functional limitation of the classic Blandy design is the proximal pedicle pulling the neomeatus posteriorly, resulting in:
- A retrusive (posteriorly displaced) neomeatus.
- An inward urinary stream that sprays the perineum or vagina rather than directing anteriorly.
- Urinary spraying reported in 2 / 7 (29%) of VFU patients in Higuchi 2026; not reported with BMG urethroplasty in the same series.[6]
This is the rationale for the lateral-based flap modification, which keeps the neomeatus orthotopic and preserves normal stream direction.[1]
Complications
- Stricture recurrence — 0–43% across series; late recurrences at ≥ 5 yr documented.[15][17]
- De novo SUI — 0–14%; mostly mild and PFPT-responsive; persistent SUI may require TOT or PVS.[2][5]
- Retrusive meatus / inward stream — specific to the classic U-flap.[1]
- Urinary spraying — VFU-specific; not reported with BMG urethroplasty.[6]
- De novo urgency / urge incontinence — reported even with technically successful repairs.[2][10]
- Urethrovaginal fistula — rare; risk reduced by multi-layer closure and Martius interposition.[9][13]
- Need for CIC — occasional (1 / 6 in Simonato).[9]
Comparison with Alternatives
| Feature | Blandy U-Flap | Lateral-Based Flap | Dorsal Onlay BMG | Ventral Onlay BMG |
|---|---|---|---|---|
| Tissue source | Anterior vaginal wall | Anterior vaginal wall | Buccal mucosa | Buccal mucosa |
| Blood supply | Pedicled (proximal base) | Pedicled (lateral base) | Free graft | Free graft |
| Meatal position | Risk of retrusive | Orthotopic | Orthotopic | Orthotopic |
| Urinary spraying | Reported | Not reported | Not reported | Not reported |
| Stricture location | Distal / mid | Distal / mid / pan | Any | Any |
| Reported success | 57–100% | 83–100% | 87–92% | 89–98% |
| Donor-site morbidity | None (same field) | None | Oral | Oral |
| Vaginal-tissue health required | Yes | Yes | No | No |
A 2026 meta-analysis (n = 319) found no significant difference between dorsal and ventral onlay BMG in success rate (RR 1.00; 95% CI 0.91–1.10), Qmax, PVR, or AUA score.[20] AUA 2023 frames urethroplasty success in women as 69–95% depending on technique, with technique selection driven by surgeon experience.[21]
When to Choose the Blandy U-Flap
- Stricture is distal or mid-urethral.[4][6]
- Anterior vaginal wall is healthy and well-estrogenized (no LS).[4][8]
- Surgeon prefers to avoid BMG donor-site morbidity.[19]
- A pedicled (vs free-graft) reconstruction is preferred.
Given the retrusive-meatus / spraying signal, many contemporary surgeons prefer the lateral-based flap modification or BMG urethroplasty when the stricture extends beyond the distal urethra.[1][6][18]
Postoperative Management
- Urethral catheter 10–21 days (surgeon preference).[2][10]
- Voiding trial after catheter removal.
- Uroflowmetry, PVR, and cystoscopy at 3–6 mo.
- Topical estrogen in postmenopausal women.[8]
- Long-term surveillance is essential — late recurrences ≥ 5 yr documented.[15]
Summary
The Blandy U-flap is the foundational ventral-onlay vaginal-flap urethroplasty for FUS — pedicled, donor-site-free, distal / mid-urethral, with reported success of 57–100% across small series. Its defining limitation is retrusive meatus and inward urinary stream from the proximal-pedicled design, which has driven adoption of the lateral-based Romero-Maroto / Simonato modification and the increasing preference for BMG urethroplasty when the stricture extends beyond the distal urethra or when local tissue is unhealthy.[1][4][5][6]
Videos
References
1. Romero-Maroto J, Verdú-Verdú L, Gómez-Pérez L, et al. Lateral-based anterior vaginal wall flap in the treatment of female urethral stricture: efficacy and safety. Eur Urol. 2018;73(1):123-128. doi:10.1016/j.eururo.2016.09.029.
2. Hajebrahimi S, Maroufi H, Mostafaei H, Salehi-Pourmehr H. Reconstruction of the urethra with an anterior vaginal mucosal flap in female urethral stricture. Int Urogynecol J. 2019;30(12):2055-2060. doi:10.1007/s00192-019-03910-3.
3. Waterloos M, Verla W. Female urethroplasty: a practical guide emphasizing diagnosis and surgical treatment of female urethral stricture disease. Biomed Res Int. 2019;2019:6715257. doi:10.1155/2019/6715257.
4. Bouchard B, Campeau L. Surgery for female urethral stricture. Neurourol Urodyn. 2025;44(1):51-62. doi:10.1002/nau.25358.
5. Chakraborty JN, Chawla A, Vyas N. Surgical interventions in female urethral strictures: a comprehensive literature review. Int Urogynecol J. 2022;33(3):459-485. doi:10.1007/s00192-021-04906-8.
6. Higuchi M, Horiguchi A, Ashiya M, et al. Vaginal flap urethroplasty and dorsal onlay buccal mucosal graft urethroplasty for female urethral stricture: a single-center experience. Int J Urol. 2026;33(5):e70477. doi:10.1111/iju.70477.
7. Önol FF, Antar B, Köse O, Erdem MR, Önol ŞY. Techniques and results of urethroplasty for female urethral strictures: our experience with 17 patients. Urology. 2011;77(6):1318-1324. doi:10.1016/j.urology.2011.01.017.
8. West C, Lawrence A. Female urethroplasty: contemporary thinking. World J Urol. 2019;37(4):619-629. doi:10.1007/s00345-018-2564-4.
9. Simonato A, Varca V, Esposito M, Carmignani G. Vaginal flap urethroplasty for wide female stricture disease. J Urol. 2010;184(4):1381-1385. doi:10.1016/j.juro.2010.06.042.
10. Gormley EA. Vaginal flap urethroplasty for female urethral stricture disease. Neurourol Urodyn. 2010;29 Suppl 1:S42-S45. doi:10.1002/nau.20814.
11. Faiena I, Koprowski C, Tunuguntla H. Female urethral reconstruction. J Urol. 2016;195(3):557-567. doi:10.1016/j.juro.2015.07.124.
12. Katiyar VK, Sood R, Sharma U, et al. Critical analysis of outcome between ventral and dorsal onlay urethroplasty in female urethral stricture. Urology. 2021;157:79-84. doi:10.1016/j.urology.2021.05.021.
13. Blaivas JG, Heritz DM. Vaginal flap reconstruction of the urethra and vesical neck in women: a report of 49 cases. J Urol. 1996;155(3):1014-1017.
14. Blaivas JG. Vaginal flap urethral reconstruction: an alternative to the bladder flap neourethra. J Urol. 1989;141(3):542-545. doi:10.1016/s0022-5347(17)40887-1.
15. Blaivas JG, Santos JA, Tsui JF, et al. Management of urethral stricture in women. J Urol. 2012;188(5):1778-1782. doi:10.1016/j.juro.2012.07.042.
16. Flisser AJ, Blaivas JG. Outcome of urethral reconstructive surgery in a series of 74 women. J Urol. 2003;169(6):2246-2249. doi:10.1097/01.ju.0000061763.88247.16.
17. Kowalik C, Stoffel JT, Zinman L, Vanni AJ, Buckley JC. Intermediate outcomes after female urethral reconstruction: graft vs flap. Urology. 2014;83(5):1181-1185. doi:10.1016/j.urology.2013.12.052.
18. Savun M, Cubuk A, Colakoglu Y, Aksakal YN, Simsek A. Comparative analysis of dorsal and ventral onlay urethroplasty with buccal mucosal graft in female urethral strictures: a multi-center study. Int Urogynecol J. 2026;37(2):511-516. doi:10.1007/s00192-025-06479-2.
19. Borchert A, Jamil M, Perkins S, Raffee S, Atiemo H. Vaginal free graft dorsal onlay urethroplasty. Urology. 2022;159:256. doi:10.1016/j.urology.2021.06.004.
20. Li X, Zhao X, Li Z, et al. Dorsal versus ventral onlay buccal mucosal graft urethroplasty in female urethral stricture: a meta-analysis. Int Urogynecol J. 2026. doi:10.1007/s00192-026-06516-8.
21. Wessells H, Morey A, Souter L, Rahimi L, Vanni A. Urethral stricture disease guideline amendment (2023). J Urol. 2023;210(1):64-71. doi:10.1097/JU.0000000000003482.