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Liquid / Minced Buccal Mucosal Graft

Liquid or minced buccal mucosal graft is an emerging technique in which harvested buccal mucosal tissue is minced into small fragments or enzymatically dissociated and then applied to the urethral stricture bed, analogous to cell-rich matrix techniques in other fields. Early experimental and clinical data suggest the approach may allow graft placement via minimally invasive or endoscopic methods. This technique remains investigational and is not yet in routine clinical use.

Indications​

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Technique Overview​

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Key Steps​

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Outcomes & Evidence​

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References​

  1. Fok KS, de la Rosette JJ, Cornu JN. "Endoscopic treatment of urethral strictures using autologous buccal mucosa: a systematic review." J Endourol. 2020;34(3):249–57. PMID: 31902245
  2. Virasoro R, DeLong JM, Smith TG, et al. "Minced buccal mucosal graft placement via endoscopic approach for urethral stricture disease." Urology. 2020;142:175–80. PMID: 32426294