Intracavernosal Injections (ICI)

Intracavernosal injection of vasoactive agents directly into the corpus cavernosum produces erection independent of neurogenic stimulation, making ICI the gold standard pharmacotherapy for post-prostatectomy erectile dysfunction when oral PDE5 inhibitors fail. Alprostadil (prostaglandin E1) monotherapy and Trimix (papaverine, phentolamine, alprostadil) are the most commonly used formulations, with efficacy rates of 70–90%.

Indications

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Agents & Formulations

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Technique Overview

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Outcomes & Evidence

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References

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